The Role of iPSC-Derived Microglia in Research and Drug Discovery

Microglia, primary immune cells in the brain and spinal cord, can both aid the brain’s immune system and contribute to neurodegenerative diseases like Alzheimer’s, according to Dr. Tilman. These cells, created from reprogrammed iPSC cells from blood or skin, maintain the donor’s phenotypic characteristics. Axol generates microglia to be used in research and applies rigorous quality control for their production. Dr Tilman predicts that exploring functional QC will improve trust in their cells’ physiological relevance.